Sinonasal Outcome Test (SNOT-22)
22-item questionnaire measuring the impact of chronic rhinosinusitis symptoms on quality of life.
Switch how results are explained
Mild sinonasal symptom burden (0-20). Limited impact on daily life on this basis alone.
- Evidence grade
- B
What it is and when to use it
SNOT-22 scores 22 sinonasal, otologic, sleep and emotional symptoms by their impact over the past 15 days, from 0 (no problem) to 5 (as bad as it can be). The sum of the 22 items gives a score from 0 to 110.
How to interpret it
0–20 mild; 21–50 moderate; 51–110 severe (Toma and Hopkins, 2016). The absolute score indicates baseline severity, but the minimal clinically important difference is 8.9 points: a change of this magnitude between two administrations is what is considered clinically meaningful — for example after treatment or surgery — more so than any single absolute total.
Limitations and when not to use it
This is a self-administered questionnaire reflecting the patient's subjective perception over the preceding 15 days; it does not replace nasal endoscopy or imaging. The otologic and emotional items are not specific to sinonasal disease and may be influenced by comorbidities.
Formulas and cut-offs are from the original authors of each score; see the references.
Last reviewed: June 2026
References
- Hopkins C, Gillett S, Slack R, Lund VJ, Browne JP. Psychometric validity of the 22-item Sinonasal Outcome Test. Clin Otolaryngol. 2009;34(5):447-454. PMID:19793277
- Toma S, Hopkins C. Stratification of SNOT-22 scores into mild, moderate or severe and relationship with other subjective instruments. Rhinology. 2016;54(2):129-133. PMID:27017484